RELEVANT LITERATURE



Melke J, Goubran-Botros H, Chaste P, et al. Abnormal melatonin synthesis in autism spectrum disorders. Molecular Psychiatry. 2008;13(1):90-98. doi:10.1038/sj.mp.4002016.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2199264/

Grabrucker AM. Environmental Factors in Autism. Frontiers in Psychiatry. 2012;3:118. doi:10.3389/fpsyt.2012.00118.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548163/pdf/fpsyt-03-00118.pdf

Hardeland R. Neurobiology, Pathophysiology, and Treatment of Melatonin Deficiency and Dysfunction. The Scientific World Journal. 2012;2012:640389. doi:10.1100/2012/640389.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354573/pdf/TSWJ2012-640389.pdf

Tordjman S, Najjar I, Bellissant E, et al. Advances in the Research of Melatonin in Autism Spectrum Disorders: Literature Review and New Perspectives. International Journal of Molecular Sciences. 2013;14(10):20508-20542. doi:10.3390/ijms141020508.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821628/pdf/ijms-14-20508.pdf

Tordjman S, Davlantis KS, Georgieff N, et al. Autism as a Disorder of Biological and Behavioral Rhythms: Toward New Therapeutic Perspectives. Frontiers in Pediatrics. 2015;3:1. doi:10.3389/fped.2015.00001.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337381/pdf/fped-03-00001.pdf

Sánchez A, Calpena AC, Clares B. Evaluating the Oxidative Stress in Inflammation: Role of Melatonin. Haenen G, ed. International Journal of Molecular Sciences. 2015;16(8):16981-17004. doi:10.3390/ijms160816981.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581180/pdf/ijms-16-16981.pdf

Anderson G, Maes M. Redox Regulation and the Autistic Spectrum: Role of Tryptophan Catabolites, Immuno-inflammation, Autoimmunity and the Amygdala. Current Neuropharmacology. 2014;12(2):148-167. doi:10.2174/1570159X11666131120223757.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964746/pdf/CN-12-148.pdf

Lin G-J, Huang S-H, Chen S-J, Wang C-H, Chang D-M, Sytwu H-K. Modulation by Melatonin of the Pathogenesis of Inflammatory Autoimmune Diseases. International Journal of Molecular Sciences. 2013;14(6):11742-11766. doi:10.3390/ijms140611742.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709754/pdf/ijms-14-11742.pdf

Carrillo-Vico A, Lardone PJ, Álvarez-Sánchez N, Rodríguez-Rodríguez A, Guerrero JM. Melatonin: Buffering the Immune System. International Journal of Molecular Sciences. 2013;14(4):8638-8683. doi:10.3390/ijms14048638.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645767/pdf/ijms-14-08638.pdf

Espino J, Pariente JA, Rodríguez AB. Oxidative Stress and Immunosenescence: Therapeutic Effects of Melatonin. Oxidative Medicine and Cellular Longevity. 2012;2012:670294. doi:10.1155/2012/670294.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549369/pdf/OXIMED2012-670294.pdf

Veatch OJ, Pendergast JS, Allen MJ, et al. Genetic Variation in Melatonin Pathway Enzymes in Children with Autism Spectrum Disorder and Comorbid Sleep Onset Delay. Journal of autism and developmental disorders. 2015;45(1):100-110. doi:10.1007/s10803-014-2197-4.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289108/pdf/nihms616238.pdf

Jonsson L, Ljunggren E, Bremer A, et al. Mutation screening of melatonin-related genes in patients with autism spectrum disorders. BMC Medical Genomics. 2010;3:10. doi:10.1186/1755-8794-3-10.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020629/pdf/1755-8794-3-10.pdf

Russo AJ, Bazin AP, Bigega R, et al. Plasma Copper and Zinc Concentration in Individuals with Autism Correlate with Selected Symptom Severity. Nutrition and Metabolic Insights. 2012;5:41-47. doi:10.4137/NMI.S8761.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698472/pdf/nmi-5-2012-041.pdf

Konturek SJ, Konturek PC, Brzozowski T, Bubenik GA. Role of melatonin in upper gastrointestinal tract.
J Physiol Pharmacol. 2007 Dec;58 Suppl 6:23-52
www.jpp.krakow.pl/journal/archive/12_07_s6/pdf/23_12_07_s6_article.pdf


Vela G, Stark P, Socha M, Sauer AK, et al. Zinc in Gut-Brain Interactions in Autism and Neurological Disorders. Neural Plasticity 2015, 15 pages.
http://dx.doi.org/10.1155/2015/972791

Bjorklund G. The Role of Zinc and Copper in Autism Spectrum Disorders. Acta Neurobiol Exp 2013, 73: 225-236.
http://www.ane.pl/linkout.php?pii=7315

Sarti P, Magnifico MC, Altieri F, Mastronicola D, Arese M. New Evidence for Cross Talk Between Melatonin and Mitochondria Mediated by a Circadian-Compatible Interaction with Nitric Oxide. Int J Mol Sci. 2013, 14: 11259-11276; doi:10.3390/ijms140611259
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709731/pdf/ijms-14-11259.pdf

Carrasco C, Rodriguez AB, Pariente JA. Melatonin as a Stabilizer of Mitochondrial Function: Role in Disease and Aging. Turk J Biol 2015, 39: 822-831; doi:10.3906/biy-1504-26.
http://journals.tubitak.gov.tr/biology/issues/biy-15-39-6/biy-39-6-3-1504-26.pdf

Arons MH, Lee K, Thynne CJ, Kim SA, et al. Shank3 is a part of a Zinc-Sensitive Signaling System That Regulates Excitatory Synaptic Strength. J Neurosci 2016, 36(35): 9124-9134.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005722/pdf/zns9124.pdf

Pagan C, Goubran-Botros H, Delorme R, et al. Disruption of Melatonin Synthesis is Associated with Impaired 14-3-3 and miR-451 Levels in Patients with Autism Spectrum Disorders. Nature 2017, 7: 2096-2107; doi:10.1038/s41598-017-02152-x.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437096/pdf/41598_2017_Article_2152.pdf